GMP,药品,药学,制药,新药,色谱,药品生产,中药,药材,原料药,医药,中间体,药用辅料

下列药物属于哪一类药物。属于孕妇用药ABCD四类中的哪一类

时间: 2008-09-18 09:02:00 作者: 来源: 字号:
包括:得力多。妥泰。纷乐。美卓乐。以上四种药属于孕妇用药ABCD四类中的哪一类?
?????似乎是道考题啊?????
A级:在有对照组的研究中,在妊娠3个月的妇女未见到对胎儿危害的迹象(并且也没有对其后6个月的危害性的证据),可能对胎儿的影响甚微。
B级:在动物繁殖性研究中(并未进行孕妇的对照研究),未见到对胎儿的影响。在动物繁殖性研究中表现有副作用,这些副作用并未在妊娠3个月的妇女得到证实(也没有对其后6个月的危害性的证据)。
C级:在动物的研究证明它有对胎儿的副作用(致畸或杀死胚胎)但并未在对照组的妇女进行研究,或没有在妇女和动物并行地进行研究。本类药物只有在权衡了对妇女的好处大于对胎儿的危害之后,方可应用。

D级:有对胎儿的危害性的明确证据,尽管有危害性,但孕妇用药后有绝对的好处(例如孕妇受到死亡的威胁或患有严重的疾病,因此需用它,如应用其他药物虽然安全但无效)。
X级:在动物或人的研究表明它可使胎儿异常。或根据经验认为在人,或在人及在动物,是有危害性的。在孕妇应用这类药物显然是无益的。本类药物禁用于妊娠或将妊娠的患者。

药物拼音缩写 TBC
药物中文名 托吡酯
药物英文名 Topiramate
药物分类 C
药物商品名 妥泰
药物注释:危害性 动物研究证明药物对胎儿有危害性(致畸或胚胎死亡等),或尚无设对照的妊娠妇女研究,或尚未对妊娠妇女及动物进行研究。本类药物只有在权衡对孕妇的益处大于对胎儿的危害之后方可使用
说明书上没有么?希望以下信息有所帮助
Tegretol®
carbamazepine
Carbamazepine can cause fetal harm when administered to a pregnant woman.
In humans, transplacental passage of carbamazepine is rapid (30-60 minutes), and the drug isaccumulated in the fetal tissues, with higher levels found in liver and kidney than in brain and lung.
TOPAMAX攵
(topiramate)
Pregnancy: Pregnancy Category C.
PLAQUENIL®
HYDROXYCHLOROQUINE SULFATE
Usage in Pregnancy—Usage of this drug during pregnancy should be avoided except in
the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the possible hazard. It should be noted that radioactively-tagged chloroquine administered intravenously to pregnant, pigmented CBA mice passed rapidly across the placenta.
It accumulated selectively in the melanin structures of the fetal eyes and was retained in the ocular tissues for five months after the drug had been eliminated from the rest of the body.
MEDROL®
Usage in pregnancy: Since adequate human reproduction studies have not been done with corticosteroids, the use of these drugs in pregnancy, nursing mothers or women of childbearing potential requires that the possible benefits of the drug be weighed against the potential hazards to the mother and embryo or fetus. Infants born of mothers who have received substantial doses of corticosteroids during pregnancy,should be carefully observed for signs of hypoadrenalism.
Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium. These effects are less likely to occur with the synthetic derivatives except when used in large doses. Dietary salt restriction and potassium supplementation may be necessary. All corticosteroids increase calcium excretion
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