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Monograph Number: 2255
Title: Chromium Picolinate
CAS Registry Number: 14639-25-9
CAS Name: Tris(2-pyridinecarboxylato-N1,O2)chromium
Additional Names: chromium(III) trispicolinate
Molecular Formula: C18H12CrN3O6
Molecular Weight: 418.30.
Percent Composition: C 51.68%, H 2.89%, Cr 12.43%, N 10.05%, O 22.95%
Literature References: Biologically active form of chromium. General prepn, chemical and biological properties: G. W. Evans, D. J. Pouchnik, J. Inorg. Biochem. 49, 177 (1993). Clinical effect on insulin metabolism: G. W. Evans, Int. J. Biosocial Med. Res. 11, 163 (1989). Clinical evaluation of lipid-lowering activity: R. I. Press et al., West. J. Med. 152, 41 (1990). Clinical pharmacokinetics: M. L. Gargas et al., Drug Metab. Disposit. 22, 522 (1994). Use as veterinary diet supplement: M. D. Lindemann et al., J. Animal Sci. 73, 457 (1995). Review of clinical pharmacology: M. F. McCarty, J. Appl. Nutr. 43, 58-66 (1991); idem, J. Optimal Nutr. 2, 36-53 (1993).
Properties: Lipophilic. Soly: water (pH 7.0) 0.6 mM, chloroform 2.0 mM. uv max (water): 264 nm (aM 15546 L mol-1cm-1).
Absorption maximum: uv max (water): 264 nm (aM 15546 L mol-1cm-1)
Use: Nutritional supplement.
Monograph Number: 2255
Title: Chromium Picolinate
CAS Registry Number: 14639-25-9
CAS Name: Tris(2-pyridinecarboxylato-N1,O2)chromium
Additional Names: chromium(III) trispicolinate
Molecular Formula: C18H12CrN3O6
Molecular Weight: 418.30.
Percent Composition: C 51.68%, H 2.89%, Cr 12.43%, N 10.05%, O 22.95%
Literature References: Biologically active form of chromium. General prepn, chemical and biological properties: G. W. Evans, D. J. Pouchnik, J. Inorg. Biochem. 49, 177 (1993). Clinical effect on insulin metabolism: G. W. Evans, Int. J. Biosocial Med. Res. 11, 163 (1989). Clinical evaluation of lipid-lowering activity: R. I. Press et al., West. J. Med. 152, 41 (1990). Clinical pharmacokinetics: M. L. Gargas et al., Drug Metab. Disposit. 22, 522 (1994). Use as veterinary diet supplement: M. D. Lindemann et al., J. Animal Sci. 73, 457 (1995). Review of clinical pharmacology: M. F. McCarty, J. Appl. Nutr. 43, 58-66 (1991); idem, J. Optimal Nutr. 2, 36-53 (1993).
Properties: Lipophilic. Soly: water (pH 7.0) 0.6 mM, chloroform 2.0 mM. uv max (water): 264 nm (aM 15546 L mol-1cm-1).
Absorption maximum: uv max (water): 264 nm (aM 15546 L mol-1cm-1)
Use: Nutritional supplement.