求酒石酸的英国标准，！
General Notices
(Ph Eur monograph 0460)
C4H6O6 150.1 87-69-4
Ph Eur
DEFINITION
Tartaric acid contains not less than 99.5 per cent and not more than the equivalent of 101.0 per cent of (2R,3R)-2,3-dihydroxybutanedioic acid, calculated with reference to the dried substance.
CHARACTERS
A white or almost white, crystalline powder or colourless crystals, very soluble in water, freely soluble in alcohol.
IDENTIFICATION
A. Solution S (see Tests) is strongly acid (2.2.4).
B. It gives the reactions of tartrates (2.3.1).
TESTS
Solution S
Dissolve 5.0 g in distilled water R and dilute to 50 ml with the same solvent.
Appearance of solution
Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y6 (2.2.2, Method II).
Specific optical rotation (2.2.7)
Dissolve 5.00 g in water R and dilute to 25.0 ml with the same solvent. The specific optical rotation is + 12.0 to + 12.8.
Oxalic acid
Dissolve 0.80 g in 4 ml of water R. Add 3 ml of hydrochloric acid R and 1 g of zinc R in granules and boil for 1 min. Allow to stand for 2 min. Collect the liquid in a test-tube containing 0.25 ml of a 10 g/l solution of phenylhydrazine hydrochloride R and heat to boiling. Cool rapidly, transfer to a graduated cylinder and add an equal volume of hydrochloric acid R and 0.25 ml of a 50 g/l solution of potassium ferricyanide R. Shake and allow to stand for 30 min. Any pink colour in the solution is not more intense than that in a standard prepared at the same time in the same manner using 4 ml of a 0.1 g/l solution of oxalic acid R (350 ppm calculated as anhydrous oxalic acid).
Chlorides (2.4.4)
5 ml of solution S diluted to 15 ml with water R complies with the limit test for chlorides (100 ppm).
Sulphates (2.4.13)
10 ml of solution S diluted to 15 ml with distilled water R complies with the limit test for sulphates (150 ppm).
Calcium (2.4.3)
To 5 ml of solution S add 10 ml of a 50 g/l solution of sodium acetate R in distilled water R. The solution complies with the limit test for calcium (200 ppm).
Heavy metals (2.4.8)
2.0 g complies with limit test C for heavy metals (10 ppm). Prepare the standard using 2 ml of lead standard solution (10 ppm Pb) R.
Loss target=_blank>酒石酸(BP2007).pdf (20.95k)
General Notices
(Ph Eur monograph 0460)
C4H6O6 150.1 87-69-4
Ph Eur
DEFINITION
Tartaric acid contains not less than 99.5 per cent and not more than the equivalent of 101.0 per cent of (2R,3R)-2,3-dihydroxybutanedioic acid, calculated with reference to the dried substance.
CHARACTERS
A white or almost white, crystalline powder or colourless crystals, very soluble in water, freely soluble in alcohol.
IDENTIFICATION
A. Solution S (see Tests) is strongly acid (2.2.4).
B. It gives the reactions of tartrates (2.3.1).
TESTS
Solution S
Dissolve 5.0 g in distilled water R and dilute to 50 ml with the same solvent.
Appearance of solution
Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y6 (2.2.2, Method II).
Specific optical rotation (2.2.7)
Dissolve 5.00 g in water R and dilute to 25.0 ml with the same solvent. The specific optical rotation is + 12.0 to + 12.8.
Oxalic acid
Dissolve 0.80 g in 4 ml of water R. Add 3 ml of hydrochloric acid R and 1 g of zinc R in granules and boil for 1 min. Allow to stand for 2 min. Collect the liquid in a test-tube containing 0.25 ml of a 10 g/l solution of phenylhydrazine hydrochloride R and heat to boiling. Cool rapidly, transfer to a graduated cylinder and add an equal volume of hydrochloric acid R and 0.25 ml of a 50 g/l solution of potassium ferricyanide R. Shake and allow to stand for 30 min. Any pink colour in the solution is not more intense than that in a standard prepared at the same time in the same manner using 4 ml of a 0.1 g/l solution of oxalic acid R (350 ppm calculated as anhydrous oxalic acid).
Chlorides (2.4.4)
5 ml of solution S diluted to 15 ml with water R complies with the limit test for chlorides (100 ppm).
Sulphates (2.4.13)
10 ml of solution S diluted to 15 ml with distilled water R complies with the limit test for sulphates (150 ppm).
Calcium (2.4.3)
To 5 ml of solution S add 10 ml of a 50 g/l solution of sodium acetate R in distilled water R. The solution complies with the limit test for calcium (200 ppm).
Heavy metals (2.4.8)
2.0 g complies with limit test C for heavy metals (10 ppm). Prepare the standard using 2 ml of lead standard solution (10 ppm Pb) R.
Loss target=_blank>酒石酸(BP2007).pdf (20.95k)