Guang Pu Xue Yu Guang Pu Fen Xi. 2007 Feb;27(2):317-20.
我在ncbi上检索藻酸双酯钠的英文关键词，只找到如下一篇文献。不禁纳闷这药是中国原研的？看着药理作用降血压，降血脂，抑制血小板聚集，可是个好药。怎么名不见经传啊？？[Study on the interaction between alginic sodium diester and azur A and the application]
[Article in Chinese]
Liu YM, Li GZ, Pan F.
Chemical College of Yantai University, Yantai 264005, China. yongming_liu@163.com
Abstract
The interaction of alginic sodium diester (ASD) and azur A (AA) was studied by absorption spectra. The influence of pH and the molar ratio of AA/ASD on the spectra was investigated. The maximum binding number (N = 168) and the binding equilibrium constant (K = 3.25 x 10) of the alginic sodium diester and azur A were obtained by the theoretical model. The new method for the determination of ASD was developed by the formation of ASD-AA ion-association complex that caused the fading of the AA. The detection limit is 0.009 microg x mL(-1). The method has the advantages of simplicity, stable system, good accuracy and selectivity, and was applied to the determination of alginic sodium diester in tablets with satisfactory results. 中国原创的药其实很多，关键是连中国人自己也不相信。 这药我医院在用，但就效果来说真的不出色，关于其相关实验我还真没仔细查阅过，很希望了解的人给点讲解。对此药困惑中…… 这个药物我在最新版本Martindale中也没有找到，很有意思吧？？ 中国海洋大学的。在国外没上市自然搜不到。 我买了一瓶，天津太平洋制药的，100片。哪位用过？有何严重副作用？
我在ncbi上检索藻酸双酯钠的英文关键词，只找到如下一篇文献。不禁纳闷这药是中国原研的？看着药理作用降血压，降血脂，抑制血小板聚集，可是个好药。怎么名不见经传啊？？[Study on the interaction between alginic sodium diester and azur A and the application]
[Article in Chinese]
Liu YM, Li GZ, Pan F.
Chemical College of Yantai University, Yantai 264005, China. yongming_liu@163.com
Abstract
The interaction of alginic sodium diester (ASD) and azur A (AA) was studied by absorption spectra. The influence of pH and the molar ratio of AA/ASD on the spectra was investigated. The maximum binding number (N = 168) and the binding equilibrium constant (K = 3.25 x 10) of the alginic sodium diester and azur A were obtained by the theoretical model. The new method for the determination of ASD was developed by the formation of ASD-AA ion-association complex that caused the fading of the AA. The detection limit is 0.009 microg x mL(-1). The method has the advantages of simplicity, stable system, good accuracy and selectivity, and was applied to the determination of alginic sodium diester in tablets with satisfactory results. 中国原创的药其实很多，关键是连中国人自己也不相信。 这药我医院在用，但就效果来说真的不出色，关于其相关实验我还真没仔细查阅过，很希望了解的人给点讲解。对此药困惑中…… 这个药物我在最新版本Martindale中也没有找到，很有意思吧？？ 中国海洋大学的。在国外没上市自然搜不到。 我买了一瓶，天津太平洋制药的，100片。哪位用过？有何严重副作用？