本人最近上美国药典查找一些药用辅料标准,但对鉴别检查等项目里面一些“TS”和“CS”字母不了解具体是表示的什么意思。
比如:Color of solution— Dissolve 1 g in alcohol, dilute with alcohol to 10 mL, and mix (Methylparaben solution). This solution is clear and not more intensely colored than alcohol or a solution prepared immediately before use by mixing 2.4 mL of ferric chloride CS, 1.0 mL of cobaltous chloride CS, and 0.4 mL of cupric sulfate CS with 0.3 N hydrochloric acid to make 10 mL, and diluting 5 mL of this solution with 0.3 N hydrochloric acid to make 100 mL. Make the comparison by viewing the solutions downward in matched color-comparison tubes against a white surface (see Color and Achromicity 631 ).
Acidity— To 2 mL of Methylparaben solution prepared in the Color of solution test add 3 mL of alcohol, 5 mL of carbon dioxide-free water, and 0.1 mL of bromocresol greenTS, and titrate with 0.10 N sodium hydroxide: not more than 0.1 mL is required to produce a blue color.
这段里面的“cupric sulfate CS ”和“bromocresol greenTS”分别是指“硫酸铜什么?”“溴甲酚绿什么?”
还有:1 N sodium hydroxide VS又是指1N 氢氧化钠什么溶液?
回答你的第2个问题:N为当量浓度,其与摩尔浓度的换算是:
酸的当量=酸的分子量/酸分子中被金属置换的氢原子数。
碱的当量=碱的分子量/碱分子中所含氢氧根数。
盐的当量=盐的分子量/盐分子中金属原子数*金属价数:
即:1N 氢氧化钠=1/1 mol/L=1 mol/L
1N硫酸=1/2mol/L=0.5mol/L
详见:
呵呵,可能是我问的方式不对,我要问的问题是:上面美国药典中的“cupric sulfate CS ” “bromocresol greenTS” “sodium hydroxide VS ” 中的“CS ”、“TS”、“VS”分别指的是什么类型溶液?
CS:比色液,是colorimetric solution的缩写。
TS:试液,是Test Solution的缩写。
VS:滴定液,是volumetric solution的缩写。
所以上述应该是硫酸铜比色液,溴甲酚绿试液,氢氧化钠滴定液,这些溶液都可以在Reagent中找到具体的配制方法。
噢,呵呵,!
比如:Color of solution— Dissolve 1 g in alcohol, dilute with alcohol to 10 mL, and mix (Methylparaben solution). This solution is clear and not more intensely colored than alcohol or a solution prepared immediately before use by mixing 2.4 mL of ferric chloride CS, 1.0 mL of cobaltous chloride CS, and 0.4 mL of cupric sulfate CS with 0.3 N hydrochloric acid to make 10 mL, and diluting 5 mL of this solution with 0.3 N hydrochloric acid to make 100 mL. Make the comparison by viewing the solutions downward in matched color-comparison tubes against a white surface (see Color and Achromicity 631 ).
Acidity— To 2 mL of Methylparaben solution prepared in the Color of solution test add 3 mL of alcohol, 5 mL of carbon dioxide-free water, and 0.1 mL of bromocresol greenTS, and titrate with 0.10 N sodium hydroxide: not more than 0.1 mL is required to produce a blue color.
这段里面的“cupric sulfate CS ”和“bromocresol greenTS”分别是指“硫酸铜什么?”“溴甲酚绿什么?”
还有:1 N sodium hydroxide VS又是指1N 氢氧化钠什么溶液?
回答你的第2个问题:N为当量浓度,其与摩尔浓度的换算是:
酸的当量=酸的分子量/酸分子中被金属置换的氢原子数。
碱的当量=碱的分子量/碱分子中所含氢氧根数。
盐的当量=盐的分子量/盐分子中金属原子数*金属价数:
即:1N 氢氧化钠=1/1 mol/L=1 mol/L
1N硫酸=1/2mol/L=0.5mol/L
详见:
呵呵,可能是我问的方式不对,我要问的问题是:上面美国药典中的“cupric sulfate CS ” “bromocresol greenTS” “sodium hydroxide VS ” 中的“CS ”、“TS”、“VS”分别指的是什么类型溶液?
CS:比色液,是colorimetric solution的缩写。
TS:试液,是Test Solution的缩写。
VS:滴定液,是volumetric solution的缩写。
所以上述应该是硫酸铜比色液,溴甲酚绿试液,氢氧化钠滴定液,这些溶液都可以在Reagent中找到具体的配制方法。
噢,呵呵,!